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Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: Phenotypic and genotypic analyses

机译：肿瘤胸苷酸合酶和p53在接受氟尿嘧啶化疗的转移性结直肠癌患者中的预后价值：表型和基因型分析

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Purpose: The aim of this multicenter prospective study was to evaluate the role of intratumoral parameters related to fluorouracil (FU) sensitivity in 103 metastatic colorectal cancer patients receiving FU-folinic acid.

机译：目的：这项多中心前瞻性研究的目的是评估与氟尿嘧啶（FU）敏感性相关的肿瘤内参数在103名接受FU-亚叶酸转移性结直肠癌患者中的作用。

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作者
Etienne, Marie-Christine; Chazal, Maurice; Laurent-Puig, Pierre; Magne, Nicolas; Rosty, Christophe; Formento, Jean-Louis; Francoual, Mireille; Formento, Patricia; Renee, Nicole; Chamorey, Emmanuel; Bourgeon, Andre´; Seitz, Jean-Francois; Delpero, Jean-Robert; Letoublon, Christian; Pezet, Denis; Milano, Gerard;
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年度 2002
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正文语种 eng
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1. Prognostic Value of Tumoral Thymidylate Synthase and p53 in Metastatic Colorectal Cancer Patients Receiving Fluorouracil-Based Chemotherapy: Phenotypic and Genotypic Analyses. [J] . Etienne MC, Chazal M, Laurent Puig P, Journal of Clinical Oncology . 2002,第12期

机译：肿瘤胸苷酸合酶和p53在接受氟尿嘧啶为基础的化疗的转移性结直肠癌患者中的预后价值：表型和基因型分析。
2. Tumor thymidylate synthase 1494del6 genotype as a prognostic factor in colorectal cancer patients receiving fluorouracil-based adjuvant treatment. [J] . Dotor E, Cuatrecases M, Martinez Iniesta M, Journal of Clinical Oncology . 2006,第10期

机译：肿瘤胸苷酸合酶1494del6基因型作为接受基于氟尿嘧啶的辅助治疗的大肠癌患者的预后因素。
3. Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. [J] . Edler David, Glimelius Bengt, Hallstrom Marja, Journal of Clinical Oncology . 2002,第7期

机译：胸苷酸合酶在大肠癌中的表达：辅助基于氟尿嘧啶的化疗获益的预后和预测指标。
4. High-Depth Sequencing of Over 750 Genes Supports Linear Progression of Primary Tumors and Metastases in the Majority of Patients with Liver-Limited Metastatic Colorectal Cancer [C] . Simeen Malik, Iain Beehuat Tan, Kalpana Ramnarayanan, International Molecular Medicine Tri-Conference. . 2015

机译：超过750个基因的高深度测序支持肝脏有限转移性结直肠癌大多数患者的原发性肿瘤和转移的线性进展
5. Impact of Erythropoiesis Stimulating Agents on Survival and Risk of Venous Thromboembolism Among Patients with Colorectal Cancer Receiving Chemotherapy. [D] . Sato, Masayo. 2012

机译：红细胞生成刺激剂对接受化疗的结直肠癌患者生存率和静脉血栓栓塞风险的影响。
6. Circulating Tumor Cell Count Is a Prognostic Factor in Metastatic Colorectal Cancer Patients Receiving First-Line Chemotherapy Plus Bevacizumab: A Spanish Cooperative Group for the Treatment of Digestive Tumors Study [O] . Javier Sastre, M. Luisa Maestro, Auxiliadora Gómez-España, 2012

机译：循环肿瘤细胞计数是接受一线化疗加贝伐单抗治疗的转移性结直肠癌患者的预后因素：西班牙合作组织用于消化道肿瘤的研究
7. Prognost ic Value of Tumoral Thymidylate Synthase and p53 in Metastat ic Colorecta l Cancer Pat ients Receiv ing Fluorourac i l-Based Chemotherapy: Phenotypic and Genotypic Analyses [O] . Marie-christine Etienne Maurice Chazal, Mireille Francoual, Patricia Formento, 2016

机译：肿瘤胸苷酸合成酶和p53在癌症结直肠癌患者中的预后价值接受基于氟尿嘧啶的化疗：表型和基因型分析

Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: Phenotypic and genotypic analyses

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